Endocrine Abstracts

Introduction: Biotin-streptavidin detection method is used in a majority of commercial immunoassay. Biotinylated antibodies (capture antibodies) bind strongly to streptavidin that anchors those antibodies to the solid phase of the assay. Thus, high biotin concentration in the serum interferes with this bond and alters the expected results. Clinical history of patient and additional laboratory test is important for troubleshooting of discordant thyroid function test result....

Introduction: Diagnosis of hypoglycemia in non-diabetics is challenging in most of the cases. Appropriate diagnosis is possible only after taking proper history and performing appropriate laboratory investigation in appropriate time. The purpose of this study is to find the spectrum of etiology of hypoglycemia in non-diabetics in a tertiary hospital in a developing world with limited resources. This may help physicians working in similar situations.Mater...